SkinCeuticals Metacell Renewal B3 utilizes a patent-pending aqueous emulsion to deliver a high concentration of 5% niacinamide combined with tri-peptide concentrate and 15% glycerin to correct early symptoms of photoaging. While symptoms of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely-aged appearance.